Yigit Akin,1 Selcuk Yucel21Department of Urology, Harran University School of Medicine, Sanliurfa, Turkey; 2Department of Urology, Acibadem University School of Medicine, Istanbul, TurkeyIntroduction: Extracorporeal shock ej10 wave lithotripsy (ESWL) is a well-known and successful treatment modality.In addition, it can be used in premature infants.
Discovery of Bis-Imidazoline Derivatives as New CXCR4 Ligands
The chemokine receptor CXCR4 and its ligand CXCL12 regulate leukocyte trafficking, homeostasis and functions and are potential therapeutic targets in many diseases such as HIV-1 infection and cancers.Here, we identified new CXCR4 ligands in the CERMN chemical library using a FRET-based high-throughput screening assay.These are bis-imidazoline compo
Natural products and dietary interventions on liver enzymes: an umbrella review and evidence map
BackgroundThe association between natural products and dietary interventions on liver enzymes is unclear; therefore, this study aimed to examine their effects on liver enzymes in adults.MethodsPubMed, Embase, and Cochrane Library of Systematic Reviews databases were searched from inception until March 2023.The Assessment of Multiple Systematic Revi
The Role of Insulin-Like Growth Factor 1 in the Progression of Age-Related Hearing Loss
Aging is associated with impairment of sensorial functions and with the onset of neurodegenerative diseases.As pari passu circulating insulin-like growth factor 1 (IGF-1) bioavailability progressively decreases, we see a direct correlation with sensory impairment and cognitive performance in older humans.Age-related sensory loss is typically kupari